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The use of CMC in the pharmaceutical industry

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The use of CMC in the pharmaceutical industry

It can be used as an emulsion stabilizer for injections, a binder for tablets and a film former. CMC is a safe and reliable anticancer drug carrier through basic and animal experiments. Using CMC as a membrane material, the modified Chinese herbal medicine Yangyin Shengji San is a modified dosage form, which can be used for skin grinding surgery wounds and traumatic wounds. Animal model studies have shown that the membrane prevents wound infection and has no significant difference from gauze dressing. The membrane is superior to gauze dressing in controlling wound tissue fluid exudation and wound healing, and has the effect of reducing postoperative edema and wound stimulation. A film prepared by using polyvinyl alcohol: sodium carboxymethyl cellulose: carboxyvinyl carton at a ratio of 3:6:1 is the best prescription, and the adhesion and release rate are increased, and the mucoadhesive sustained-release film is increased. The adhesion of the agent, prolonging the residence time of the preparation in the oral cavity and the efficacy of the drug in the preparation are obviously improved. Because of its potent local anesthetic, bupivaca can sometimes produce more serious cardiovascular side effects when it is poisoned. Therefore, the clinical application of bupivacaine has been paid more and more attention to the prevention and treatment of its toxicity. Pharmacological studies have shown that CIVIC as a sustained release substance formulated with a solution of bupivacaine can significantly reduce the side effects of the drug. In PRK surgery, low-dose dicaine and non-steroidal anti-inflammatory drugs combined with CMC can significantly relieve postoperative pain. Preventing peritoneal adhesions after abdominal surgery and reducing the incidence of intestinal obstruction is one of the most concerned issues in clinical surgery. Studies have shown that CMC can significantly reduce the degree of postoperative peritoneal adhesion than sodium hyaluronate, which can be used as an effective method.

Pub Time : 2019-11-04 09:42:08 >> News list
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